Multiparametric (anatomical & functional) MR Imaging of the facial skull and neck on a patient with squamous cell carcinoma. Facial and neck are very heterogeneous regions, containing a variety of tissues that include fat, muscle, air, glandular tissue and bone. For this reason, chemical/spectral saturation and hybrid fat saturation techniques (SPAIR, SPIR, SPECIAL) suffer from inhomogeneous fat suppression that causes signal intensity dropouts, signal heterogeneity and image blurring, making the images difficult to be interpreted. STIR and Dixon/IDEAL techniques can provide robust fat suppression, even in challenging body regions such as the facial and neck (figure). STIR is a FSE acquisition and can also be used in conjunction with the DWI sequence, while Dixon/IDEAL is a technique that can be used in conjunction with both SE/FSE and GRE sequences.